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Ewing's sarcoma tumors are small, round cell tumors that arise either in bone or soft tissues. These tumors are often referred to as "Ewing sarcomas" or "pPNET" (peripheral primitive neuroectodermal tumor). The cell of origin for this family of tumors is unknown.

Sometimes patients may also have a fever. Because these symptoms are suggestive of an infection, a delay in the diagnosis of a malignancy may occur.

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